Banca de DEFESA: ANDRÉ BARBOSA DA SILVA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : ANDRÉ BARBOSA DA SILVA
DATA : 10/05/2018
HORA: 14:00
LOCAL: Superintendência Federal de Agricultura em Santa Catarina Rua João Grumiche, 117 – Bloco G São José
TÍTULO:

Diagnosis of Veterinary drugs as carry-over and contaminants in feed production lines of poultry and swine

PALAVRAS-CHAVES:

Public health; Growth promoters; Food safety; Crossed contamination; Medicated feed.

PÁGINAS: 51
GRANDE ÁREA: Ciências Agrárias
ÁREA: Medicina Veterinária
SUBÁREA: Inspeção de Produtos de Origem Animal
RESUMO:

In order to increase productivity, the current model of pigs and poultry production intends to enhance stocking and decrease the gap between lots. This scenario raise infection pressure and diseases risk in animals. To avoid this problem, routine use of drugs is applied, intensifying the possibility of residues in animal products and antimicrobials resistance. The objective of this study was to diagnose the carry-over and contaminants of veterinary drugs included in the production lines of poultry and pork feed. Samples were taken from 25 production lines of 21 establishments authorized by the Ministry of Agriculture, Livestock and Supply (MAPA) to produce medicated feed. Samples of medicated feed and feed manufacture in sequence were collected for the qualitative and quantitative analysis of 62 active principles. The samples were collected at the last shared point of the production lines, that is, at the loading of the truck or at the moment of the bagging. For sampling of the bulk feed, the loading time was divided into five intervals and in the bagged, total number of bags was divided by five. At each of these intervals, 500 grams of product were collected. Fractions of medicated feed were homogenized and composed a single sample. In the subsequent rations each of the five fractions composed a sample. For analysis, a mass spectrometer QTrap®5500 (Sciex, Foster City, CA, USA) coupled to the Agilent 1290 LC liquid chromatograph (Agilent Technologies, Inc., Santa Clara, CA, USA) was used, using analytical methodology developed and validated by MAPA, sensitive to simultaneously detect 62 active principles. In the medicated feed, 80.4% presented a concentration of active principles divergent from the prescribed dosages. In 70% of the feeds there was heterogeneity in the mixture of active principles. In subsequent rations, carry-over was greater than 1% of the dose found in 63% of the cases, with a decrease of the concentration of the active principle among the five samples collected (P < 0.05). Of the 25 analyzed lines, only one showed no contamination with other active principles. No correlations were found between the nutritional composition of the feed with the ingredient used as flush in the carry-over. The present study demonstrated that control of the use of medicaments through animal feed should be improved based in risk analyzes focused on public health, aiming not only food safety, but also sustainability.

MEMBROS DA BANCA:
Presidente - 2648941 - IVAN BIANCHI
Interno - 564.081.370-91 - JALUSA DEON KICH - EMBRAPA
Externo à Instituição - HEITOR DAGUER - UFPR