Banca de QUALIFICAÇÃO: CARLA GUIMARÃES SCHERER

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : CARLA GUIMARÃES SCHERER
DATE: 01/12/2023
TIME: 13:30
LOCAL: Web Conferência - Google Meet: meet.google.com/cym-bqcs-vot.
TITLE:

The use of dried plasma via feed can reduce the use of antimicrobials and increase productivity and quality of the inseminating dose in male swine?

KEY WORDS:

immune system, swine males, bacteriological contamination, dose durability, sperm.

PAGES: 45
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUMMARY:

In order to contribute to the reduction of the use of antimicrobials in swine farming, several compounds are being tested. Dry plasma is composed of biologically active peptides, and functional proteins, including Ig (IgA, IgG and IgM), albumin and growth factors. In addition to having high palatability, due to its mechanism of action, dry plasma has anti-inflammatory action, acting in the improvement of the remodeling of immune function. In adult male pigs, semen producers, any physiological change (stress, disease, management changes, etc.), can lead to decreased sperm quality and higher rates of bacterial contamination in ejaculates. Thus, substances that contribute to the physiological balance and that dispense with the use of antimicrobials can increase the productivity and quality of inseminating doses while favoring the reduction of the use of antimicrobials in swine farming. Given the above, the objective of this study is to verify the effect of the use of dry plasma, in association or not with antimicrobials, on the diet of boars in a semen collection regime, evaluating its effect on the immune system, on the productivity of inseminating doses and on the seminal quality (integrity of sperm and decrease in bacterial count) after refrigeration for 5 days. For this, 60 male pigs of the same genetics and housed in the same semen production center, will be divided into 4 experimental groups: boar receiving breeder feed (Group 1 - Control); boar receiving added feed from therapeutic dosages of antibiotic for 7 days (Group 2); boar receiving added feed of therapeutic dosages of antibiotic for 7 days and dry plasma for 45 days (Group 3) and boar receiving reproductive ration added from dry plasma for 45 days (Group 4). The animals will be evaluated for the production of plasma cytokines, salivary cortisol, bacterial contamination of the ejaculates (including: 16S sequencing, bacterial count and isolation, EasyKit - Bacterial concentration and antibiogram) and weekly analysis (CASA and flow cytometry) in 4 moments: on days D-2, D7, D45 and D90 days, D0 being considered the day of the beginning of treatment. In addition, throughout the entire period they will be evaluated weekly for the productivity indices of inseminating doses. In this way, we aim to establish a viable protocol for the use of dry plasma in pig breeding that can lead to a decrease in the use of antimicrobials, with improved productivity and seminal quality.

COMMITTEE MEMBERS:
Interno - 2613308 - DELANO DIAS SCHLEDER
Interna - 1046884 - ELIZABETH SCHWEGLER
Interno - 1810731 - JULIANO SANTOS GUERETZ
Presidente - ***.965.078-** - MARIANA GROKE MARQUES - EMBRAPA
Interno - 1755182 - MARIO LETTIERI TEIXEIRA
Interna - 2408296 - SORAYA REGINA SACCO