MANUFACTURING PROBIOTICS IN NANOVESICLES SUPPLEMENTED WITH MINERALS.
Bacillus subtilis; nanovesicles; Intestinal microbiota;
The present invention patent for the "MANUFACTURE OF PROBIOTICS IN NANOVESICLES SUPPLEMENTED WITH MINERALS" describes an industrial product that utilizes soy lecithin as a nanovesicle-forming agent through sonication and the incorporation of Bacillus clausii spores and minerals (iron, phosphorus, selenium, and zinc). In this way, it will be possible to use this product for promoting the growth and development of animals, preventing diseases, enhancing resistance to environmental changes, and more. Therefore, the supplementation of probiotics combined with other nutrients is an effective strategy to improve the composition of the intestinal microbiota and innate immunity, contributing to better growth performance, stress tolerance, and resistance to bacterial infections in animals during their early life stages. The applicability of this invention lies in the field of animal health and the production of large animals. The use of this product aligns with the concept of animal welfare, offering a low-cost, non-toxic, natural product, and it also allows for the release of Bacillus clausii spores to inhibit the growth of pathogens throughout the animal's small and large intestine.