Banca de QUALIFICAÇÃO: FELLIPE DE SOUZA DORNELES

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : FELLIPE DE SOUZA DORNELES
DATE: 03/12/2022
TIME: 10:00
LOCAL: Web Conferência - Google Meet: meet.google.com/hep-fyaf-hah.
TITLE:

Comparison of glomerular filtration rate (GFR) in dogs and cats through the Cockcroft-Gault and Modification of Diet in Renal Disease (MDRD) equations.

KEY WORDS:

kidneys; serum creatinine; reference; renal function.

PAGES: 45
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUMMARY:

The glomerular filtration rate (GFR) is evaluated in the clinical routine, through the clearance of some substance that must be fully filtered by the kidneys, the most commonly used being serum creatinine. In Medicine, formulas that establish the GFR based on serum creatinine are used, taking into account factors such as weight, sex and age of the patients. The project aims to use the Cockcroft-Gault formulas, which determine the GFR (mL/min): creatinine clearance = [140-age] x (weight) x K / 72 x serum creatinine, K being 0, 85 in females only, and the Modification of Diet in Renal Disease (MDRD), with GFR (mL/min/1.73m2) = 186 x (serum creatinine)-1.154 x (age)-0.203 x (0.742, if female ), used in Medicine to establish the GFR in healthy dogs and cats, in order to establish reference values. An initial sample was used retrospective data from 18 cats and 31 dogs treated at the Clinical and Surgical Practice Center of the IFC, Concórdia-SC campus. In the evaluated felines, an average of 7.08±6.55 mL/min and a coefficient of variation (CV) of 92% were obtained, using Cockcroft-Gault and 209.96±175.86 mL/min/1, 73m² and CV of 84% using MDRD. In the evaluated dogs, the average was 26.96±16.94 mL/min and CV of 63% using the Cockcroft-Gault and 210.34±134.08 mL/min/1.73m² and 64% of CV using the MDRD.

COMMITTEE MEMBERS:
Interno - 2613308 - DELANO DIAS SCHLEDER
Interna - 1046884 - ELIZABETH SCHWEGLER
Interno - 1810731 - JULIANO SANTOS GUERETZ
Interno - 2017813 - RICARDO EVANDRO MENDES
Presidente - 2408296 - SORAYA REGINA SACCO