Banca de QUALIFICAÇÃO: TAISA VANESSA OLDONI

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : TAISA VANESSA OLDONI
DATE: 03/12/2022
TIME: 08:30
LOCAL: Web Conferência - Google Meet: meet.google.com/hep-fyaf-hah.
TITLE:

3D Prototyping for Prostheses Incorporating Rationally Synthesized Compounds with Antimicrobial Activity in Application in Veterinary Medicine.

KEY WORDS:

Prosthesis-related infections; Animal models; 3D printing; Bioprint; Candida albicans infections.

PAGES: 45
BIG AREA: Ciências Agrárias
AREA: Medicina Veterinária
SUMMARY:

This project aims to develop prototypes of biofunctionalized prostheses for use in veterinary medicine containing formulations of rationally synthesized compounds (CRS) known to have antimicrobial activity for efficacy and toxicity tests in ex vivo and in vivo models. For the methodological development, pig ear skin was used for the penetrability study with a gray resin test piece containing 8-hydroxyquinoline (8-HQ). Immediately after skin preparation, the epidermal side of the sample was placed in contact with the prosthesis printed in gray resin containing 8-Hydroxyquinoline 10mg for a period of 6 hours. After this period, the skin was placed in formalin for a period of 20 days, then prepared for the production of slides for penetrability analysis. The method for determining antifungal activity was Disk Diffusion in Sabouraud agar. The prostheses were made based on the concept of planning, development and testing called “Do It Yourself” (DIY). The parts were modeled in free online software (“TinkerCAD”) and were made with gray resin in a 3D printer.

COMMITTEE MEMBERS:
Interno - 2613308 - DELANO DIAS SCHLEDER
Interna - 1046884 - ELIZABETH SCHWEGLER
Interno - 1810731 - JULIANO SANTOS GUERETZ
Presidente - 1755182 - MARIO LETTIERI TEIXEIRA
Interno - 2017813 - RICARDO EVANDRO MENDES
Interna - 2408296 - SORAYA REGINA SACCO